Testosterone Therapy Could Be a Potential Approach For Treatment of Elderly Male COVID-19 Patients- A Review

The emerging SARS-CoV-2 (2019-nCoV) is still following the increasing trend of infection worldwide with an elderly male predominance. Studies reported that majority patients COVID-19 suffer from severe testosterone deficiency and are likely to die coronavirus mainly due a less effective immune response high level pro-inflammatory cytokines, condition called cytokine storm. Testosterone (a steroid having protective anti-inflammatory properties) therapy reduces circulating levels cytokines. in management Alzheimer's disease where cytokines potent mediators inflammatory processes, aged men HIV infection. As, currently there no specific therapeutic drug targeting SARS-CoV-2, and, considering present pandemic circumstance, immunomodulatory findings previous studies, it can be hypothesized could potential approach for treatment patients. J. Bio-Sci. 29(1): 181-187, 2021 (June)